High-Throughput Data Analysis of Proteomic Mass Spectra on the Swissbiogrid

Publication Type  Book Chapter
Year of Publication  2009
Authors  Quandt, A.; Maffioletti, S.; Pautasso, C.; Stockinger, H.; Lisacek, F.; Kunszt, P.
Book Title  Handbook of Research on Computational Grid Technologies for Life Sciences, Biomedicine and Healthcare
Publisher  IGI Publishing
Abstract  Proteomics is currently one of the most promising fields in bioinformatics as it provides important insights into the protein function of organisms. Mass spectrometry is one of the techniques to study the proteome, and several software tools exist for this purpose. The chapter first introduces the protein identification problem, an important application in proteomics, then it presents a meta-computing approach for solving such problem by combining different existing predictors. The chapter presents an extendable software platform called swissPIT that combines different existing tools and exploits Grid infrastructures to speed up the data analysis process for the proteomics pipeline.
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